Does Ingestion of Tincture of Opium Notably Raise Blood Alcohol Concentration?‎

Background: Tincture of opium (TOP) is currently used for maintenance therapy in treatment of opioids addiction. It contains ethanol. The present study was conducted to assess the increase in blood alcohol concentration (BAC) in its users; a process which may interfere with breath-alcohol test performed by law enforcement or traffic police. Methods: A total of ۱۴۳ individuals were selected randomly from drug users who had been referred to an addiction treatment clinic. They were asked to undergo breath-alcohol test ۱۵, ۳۰, ۴۵, and ۶۰ min after taking their daily dosage of TOP. The resulting figures were statistically analyzed by t-test and chi-square test using SPSS for Windows. Findings: The calculated blood ethanol concentration rose to ۲۶.۳۳ ± ۱۴.۳۴, ۲۹.۱۵ ± ۶.۷۰, and ۳۳.۰۳ ± ۸.۴۶ in persons taking ۲۰, ۲۵, and ۳۰ ml TOP respectively, ۵ min after their drug ingestion. The figures turned into zero after ۱۵ min. Conclusion: Users of TOP should be reassured about its alcoholic content. Its alcoholic content cannot produce equilibrium disturbance or notable BAC. However, it is recommended that users of TOP are observed in addiction treatment centers for ۱۵ min after taking their drug to reach a higher degree of certainty about any effect of alcoholic content of TOP.

کلیدواژه ها:

Addiction ، treatment ، Tincture of opium ، Ethanol