An Investigation of the Risk Factors of Osteoporosis and the Correlation between Opium Consumption and Osteoporosis in Adults

سال انتشار: 1396
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 85

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شناسه ملی سند علمی:

JR_AHJK-9-4_005

تاریخ نمایه سازی: 12 مرداد 1403

چکیده مقاله:

Background: Osteoporosis and osteopenia are the most common metabolic bone diseases making the patients vulnerable to bone fragility and fracture. In this study, the association of opium consumption and osteoporosis adjusted for other risk factors was studied.Methods: In this cross-sectional study, ۶۱۹ cases including ۷۳ men and ۵۴۶ women referred to densitometry center in Kerman, Iran, were studied. Demographic information, history of opium consumption, medications, and other risk factors were collected using a structured questionnaire.Findings: In a univariate analysis, opium consumption, aging, and having a body mass index (BMI) lower than ۲۴ accompanied an increased chance of osteoporosis, while taking physical exercises on a daily basis reduces the chance of osteoporosis. Through multivariable analysis, the two variables of age group and BMI group turned out to be of significance; that is, the chance of osteoporosis or osteopenia in the age group of higher than ۶۰ years and ۴۵-۶۰ years being placed in one of the levels of osteoporosis or osteopenia was ۴.۹ and ۳.۱ times higher than the age groups lower than ۴۵ years, respectively, after being adjusted to the other variables.Conclusion: Considering the results of this study, though the risk of bone density reduction in the individuals consuming opium was higher, due to the disparity between opium consumption in the two sexes, the difference was not significant between the two groups, and it is proposed that studies on larger samples and in the both sexes be conducted to determine the impacts of opium on the bone density.

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نویسندگان

Zeinab Heidari

Physiology Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran

Armita Shahesmaeili

Assistant Professor, HIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran

Mohammad Reza Khajeh-Bahrami

General Practitioner, Modeling in Health Research Center, Institute of Future Studies in Health, Kerman University of Medical Sciences, Kerman, Iran

Mandana Rezazadeh-Mehrizi

Rheumatologist, Department of Rheumatology, Seyed-al-Shohada Hospital, Kerman, Iran

Mohammad Hossein Gozashti

Associate Professor, Endocrinology and Metabolism research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences Kerman, Iran

Vahid Moazed

Associate Professor, Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran

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