Synthesis of dihidroxy diazacrown compound (21C7) in water as a solvent

Under mildly acidic and pH-controled aqueous condition the aminolysis of bisepoxid by aliphatic amine as tri ethylene tetra amine is generally highly regioselective giving corresponding dihidroxy crown in 20% yield. The synthesis of last compound was performed in water in acidic condition instead organic solvents.

کلیدواژه ها:

Dihidroxy crown ، Aza crown ethers ، Bisepoxide ، Ring opening ، Beta amino alcohol