Novel method for the synthesis of pyrazolopyridines using nano-Fe(3)O(4)

A multicomponent reaction for the synthesis of pyrazolo [4, 3-e] pyridines from 3-amino-5-methylpyrazole, indan-1, 3-dione and aldehydes using nano-Fe(3)O(4) as an effective andreusable catalyst is reported. The present methodology offers several advantages, such as asimple procedure with an easy work-up, short reaction times, high yields, and the absence of anyvolatile and hazardous organic solvents.

کلیدواژه ها:

Multicomponent ، pyrazolo [4 ، 3-e] pyridines ، 3-amino-5-methylpyrazole ، indan-1 ، 3-dione ، green chemistry