Synthesis of ۲,۴,۵-tri substituted imidazole derivatives in the presence of nano kaolinsupported by Sn(IV) tetrachloride under ultrasonic conditions

Imidazole derivatives, vital in pharmacology and industry, are efficiently synthesized using a novel nanokaolin Lewisacid catalyst supported by Sn(IV) tetrachloride. This green approach confirms high yields, rapid reactions, and versatilitythrough ultrasonic methods and addresses concerns about solvent toxicity.

کلیدواژه ها:

One-pot synthesis ، ultrasonic ، Trisubstituted imidazoles ، Green chemistry ، nano kaolin