Novel in silico designed inhibitor for BTK enzyme and B-cell lymphoma treatment bynatural fragments

سال انتشار: 1403
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 48

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شناسه ملی سند علمی:

NICEC22_153

تاریخ نمایه سازی: 7 مرداد 1403

چکیده مقاله:

Bruton’s tyrosine kinase (BTK) has been discovered by its critical role in B cell receptor signalingpathway, and for inhibition of malignant B cell growth as well. In this work, we have successfully designed a newinhibitor for BTK enzyme, using natural fragments by in silico studies.

نویسندگان

Aliasghar Behzadi

Organic chemistry department, Faculty of Chemistry, Sharif university of technology, Tehran, Iran.

Alireza Fattahi

Organic chemistry department, Faculty of Chemistry, Sharif university of technology, Tehran, Iran.