Using A Plant Exosome to Improve the Biocompatibility of Zeolitic Imidazolate FrameworkNanocarriers

سال انتشار: 1403
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 111

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شناسه ملی سند علمی:

NICEC22_103

تاریخ نمایه سازی: 7 مرداد 1403

چکیده مقاله:

A novel core-shell nanocarrier consisting of doxorubicin-loaded ZIF-۸ (core) enveloped by a plantexosome (shell) was established. The proper synthesis of the nanocarrier was confirmed by physicalcharacterization. Nanoparticle coating led to a reduced hemolysis rate and enhanced immune evasion,indicating improved biocompatibility

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نویسندگان

Adeleh Saffar

Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran.

Ahmad Reza Bahrami

Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran.b Industrial Biotechnology Research Group, Institute of Biotechnology, Ferdowsi University of Mashhad, Mashhad, Iran.

Amir Sh. Saljooghi

Industrial Biotechnology Research Group, Institute of Biotechnology, Ferdowsi University of Mashhad, Mashhad, Iran.c Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran.

Maryam M. Matin

Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran.Novel Diagnostics and Therapeutics Research Group, Institute of Biotechnology, Ferdowsi University of Mashhad,Mashhad, Iran.