Design and production of a chimeric enzyme with efficient antibacterial properties onStaphylococcus aureus

Improper use of antibiotics has led to antibiotic resistance. Endolysins, such as the engineered chimericenzybiotic CSTEnz, offer a promising alternative. CSTEnz, with a Staphylococcus aureus cell wall-binding domain,displayed potent and specific lytic activity against Methicillin-resistant Staphylococcus aureus, making it apotential agent against MRSA infections.

کلیدواژه ها:

Endolysin ، Methicillin-Resistant Staphylococcus aureus ، Antibiotic Resistance ، Phage ، enzymeEngineering