Antibacterial activity, anti-adherence and anti-biofilm activities of plants extracts against Aggregatibacter actinomycetemcomitans: An in vitro study in Hilla City, Iraq

The current study was designed to establish the antibacterial efficacy of various extracts from medicinal plants. The inhibition effects of six plants including Viscus album, Apium graveolens, Melissa officinalis, Plantago ovata, Senna acutifolia, and Vitis vinifera were examined against Aggregatibacter actinomycetemcomitans, which obtained from dental caries patient. The output showed that the tested bacterial isolates were greatly sensitive to M.  officinalis and S. acutifolia and their maximum inhibition zones were ۳۵ mm and ۳۳ mm respectively. The tested bacterial isolates were greatly sensitive to M.  officinalis and S. acutifolia in comparison with the antibiotic. According to the well-diffusion test results, the crude aqueous extracts from the plants showed varying degrees of inhibition of bacterial growth. Moreover, these medicinal plant extracts were a promising group of natural product sources that can be examined to continue developing products through the use of oral medicines and health care.

کلیدواژه ها:

Antibacterial Activity ، Aggregatibacter actinomycetemcomitans ، plant extracts ، Inhibition zone