Diagnosis of oral pigmented mucosal lesion

مقدمه/ بیان مساله : Differential diagnosis of an oral pigmented lesion may include, reactive, traumatic, associated with systemic disease as well as neoplastic pathologies. A complete investigation of dental, medical and familial histories is necessary for accurate clinical diagnosis and in most cases, pathology and immunohistochemical studies may be essential for definite diagnosis. معرفی بیمار : A ۵۲-year-old woman with a greyish mucosal lesion in interdental gingiva of premolars in the maxilla extending from buccal to palatal area. The clinical differential diagnosis were peripheral giant cell granuloma and hemangioma. In radiography, there was a slight crestal bone resorption in the lesion area. The incisional biopsy and histopathology examination was under taken. In microscopy, there was aggregations of atypical melanocytes resembling epithelioid cells proliferating in the connective tissue with abundant melanin pigment formations. To exclude the possibility of the malignant melanoma immunohistochemical studies was necessary.

کلیدواژه ها:

Oral mucosal lesion ، Pigmentation ، Melanocytes ، Malignant Melanoma