A stochastic model for HIV with the use of PrEP

Pre-exposure prophylaxis (PrEP) has become a promising strategy used by uninfected individuals for the HIV prevention. The risk of infection with HIV after exposure to the virus can be understood through a stochastic framework. In this research we present a stochastic model for HIV/AIDS epidemic with the use of prophylaxis and we show that the model with random perturbation has a unique global positive solution. For a special case, we introduce an analogue, {\cal R}_{\sigma}, of the basic reproduction number. This invariant features in a theorem on almost sure exponential stability. Our results show that the disease goes extinct exponentially and almost surely whenever {\cal R}_{\sigma} stays below unity. Simulations serve to illustrate various phenomena.

کلیدواژه ها:

HIV/AIDS stochastic model ، basic reproduction number ، pre-exposure prophylaxis ، almost sure exponential stability ، extinction