Encapsulation of probiotics by Electrospinning: Advances, Challenges and future prospects

Electrospinning, a cutting-edge nanofabrication technique, holds the potential to significantly enhance the survival and efficacy of probiotics, offering innovative solutions to address challenges associated with their delivery and viability. This review abstract explores the application of electrospinning in improving probiotic viability by encapsulating them within protective nanofiber matrices. The technique allows precise control over fiber morphology, diameter, and composition, tailoring encapsulation systems to safeguard probiotics from harsh gastrointestinal conditions. Electrospun nanofibers provide a protective barrier that shields probiotics from gastric acids and digestive enzymes, enabling their controlled release within the targeted gastrointestinal segments. This controlled release not only enhances probiotic survival but also facilitates sustained colonization and interactions with the host microbiota. Challenges such as optimal polymer selection, uniform probiotic distribution, and long-term stability are discussed, along with emerging applications and future prospects. Electrospinning's potential to revolutionize probiotic delivery and efficacy marks a pivotal advancement at the intersection of nanotechnology and microbiology, promising to unlock new avenues for personalized and effective health interventions.

کلیدواژه ها:

Encapsulation ، probiotic ، Electrospinning ، Nanofibers