Quantitative and Qualitative Scintigraphic Measurement of Renal Function in Persian Cat Using ۹۹mTechnetium Ethylenedicysteine and ۹۹mTechnetium Diethylenetriaminepentaacetic
محل انتشار: دوفصلنامه جراحی دامپزشکی، دوره: 7، شماره: 1
سال انتشار: 1391
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 59
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شناسه ملی سند علمی:
JR_IJVS-7-1_005
تاریخ نمایه سازی: 8 خرداد 1403
چکیده مقاله:
Objective- To consider the use of renal scintigraphic evaluation of kidney function in Persian cat and make a comparison between ۹۹mTechnetium ethylenedicysteine and ۹۹mTechnetium diethylenetriaminepentaacetic in renal scintigraphy.Design- Descriptive studyAnimals- ۶ male healthy adult Persian cats - no clinical sign of renal disorders and prior to presentation.Procedure- The scintigraphy of right and left kidney using Gamma camera (Piker Model) and ۹۹mTc-EC and ۹۹mTc-DTPA as radiopharmaceuticals. Peak activity percentage (% PA), peak time (Tmax), half emptying-time (T۱/۲), total and individual GFR and flow and function time activity curves (TACs) are the determined parameters in this evaluation.Results- % PA, Tmax and T۱/۲ in left and right kidney for ۹۹mTc-EC and ۹۹mTc-DTPA respectively, were ۴۹/۸۶ %, ۵۰/۱ %, ۱۱/۳ min, ۱۱/۵ min, ۴/۴ min, ۴/۶ min and ۵۱/۲۷ %, ۴۹/۰۵ %, ۷/۷ min, ۸/۳ min, ۳ min, ۳/۴۳ min.Moreover the quantities of total and individual GFR for left and right kidney measured by ۹۹mTc-DTPA measured by modified Gates technique respectively, were ۱۲۵/۶۹ ml/min, ۶۴/۴۲ml/min (۵۱/۲۶ %), ۶۱/۲۴ml/min (۴۸/۷۳ %) and were in normal range defined by Gates technique.Conclusion and Clinical Relevance- normal indices obtained for listed parameters and total and individual GFR quantities can play a major role in order to diagnose kidney disorder or function deterioration and can be a background and specialized knowledge conducive to future studies.Also comparison of two radiopharmaceuticals ۹۹mTc-EC and ۹۹mTc-DTPA showed that ۹۹mTc-DTPA scintigraphy has the superiority to assess the quantities of total and individual GFR so we can use ۹۹mTc-DTPA to evaluate Glomerular filtration rate in both kidneys.
کلیدواژه ها:
نویسندگان
Darioush Vosough
Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran.