Identification and Analysis of Dyslipidemia  Risk Factors in a Population-Based Study: Data from the Fasa Persian Cohort

Background & Objectives: Dyslipidemia is a major public health issue worldwide characterized by changes in lipid index such as cholesterol, Low Density Lipoprotein (LDL), High Density Lipoprotein (HDL) and triglycerides (TG).This manuscript aimed to investigate the associated factors of dyslipidemia in Fasa Persian cohort study. Materials & Methods: This cross-sectional study was conducted on the baseline data of Fasa Persian cohort with an initial sample size of ۱۰۱۲۹ subjects (۳۵-۷۰ years old) in ۲۰۲۱ in Iran. Univariate and multivariate logistic regression models were used to assess the relationship between covariates and dyslipidemia. Results: The number of males in this study was ۴۵۷۲ and the number of females was ۵۵۵۷. The prevalence of dyslipidemia in them was ۴۰.۸% and ۲۷.۷%, respectively (p-value < ۰.۰۰۱), and the prevalence of dyslipidemia in the whole study population was ۳۴۰۷ (۳۳.۶%).  Dyslipidemia was also more common in alcoholics, opium users, smokers, high glycemic index and higher body mass index (BMI). Men were ۱.۶۸ times more likely to have dyslipidemia than women. Opium and cigarette smokers were ۱.۱۵ and ۱.۳۶ times more likely to have dyslipidemia than non-smokers, respectively. Also, as BMI increases, the likelihood of dyslipidemia becomes higher than the reference group (below ۱۸.۵), and people with a BMI greater than ۳۰ have the highest obesity range. Conclusions: This study showed that the prevalence of dyslipidemia in the studied population was higher in men than in women and several risk factors such as gender differences, body mass index, smoking and opium use are effective in the prevalence of dyslipidemia.

کلیدواژه ها:

Dyslipidemia ، Cholesterol ، High Density Lipoprotein ، Related Factors