Analysis of single umbilical artery with concurrent congenital anomaly: Is it a risk factor for poor prognosis? A cross-sectional study
سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 44
فایل این مقاله در 10 صفحه با فرمت PDF قابل دریافت می باشد
- صدور گواهی نمایه سازی
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_IJRM-22-2_005
تاریخ نمایه سازی: 25 فروردین 1403
چکیده مقاله:
Background: A single umbilical artery (SUA) may coexist with a single anomaly or multiple congenital anomalies. Although anomalies associated with SUA can primarily cause high perinatal mortality, their clinical significance has not been evaluated.
Objective: We investigated the relationship between the clinical features and the type or number of concurrent anomalies in neonates with SUA.
Materials and Methods: In this cross-sectional study, ۱۰۴ neonates with SUA were enrolled from January ۲۰۰۰ to December ۲۰۲۰ at Dongsan hospital, Daegu, South Korea. Data on the maternal history and the neonates demographic characteristics, clinical course, chromosomal analysis, and congenital anomalies, were collected.
Results: Among the neonates with SUA included, ۷۷ (۷۴.۰%) had one or more congenital anomalies; ۶۶ (۶۳.۵%) were cardiac, ۲۰ (۱۹.۲%) were genitourinary, ۱۲ (۱۱.۵%) were gastrointestinal, ۵ (۴.۸%) were central nervous system, ۱۲ (۱۱.۵%) were skeletal, and ۵ (۴.۸%) were facial anomalies. The number of concurrent anomalies ranged from ۰-۴. Neonates with SUA and concurrent gastrointestinal anomaly had a high incidence of initial positive ventilation, intubation, and inotropic drug use and lower Apgar score at ۱ min and ۵ min. ۷ (۶.۷%) neonates with SUA died. Low birth weight (odds ratio = ۶.۱۶, p = ۰.۰۵), maternal multiparity (۲.۴۱, p = ۰.۱۳), gastrointestinal anomaly (۵.۰۶, p = ۰.۱۱), and initial cardiac resuscitation (۷.۷۷, p = ۰.۱۱) were risk factors for mortality in neonates with SUA.
Conclusion: Neonates with SUA and concurrent gastrointestinal anomaly, low birth weight, maternal multiparity, and initial cardiac resuscitation had poor outcomes.
کلیدواژه ها:
نویسندگان
Na Hyun Lee
Department of Pediatrics, Keimyung University School of Medicine, Daegu, Republic of Korea.
Hee Joung Choi
Department of Pediatrics, Keimyung University School of Medicine, Daegu, Republic of Korea.
مراجع و منابع این مقاله:
لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :