Copper-Catalyzed Intramolecular N-Arylation of Dihalobenzene and Amine-Trichloroacetonitrile Adduct under Ultrasound-Irradiation

An ultrasonic-assisted, one-pot three-component intramolecular cyclization of dihalobenzene and amine-trichloroacetonitrile adduct, for the synthesis of some new N۱-substituted analogs of ۲-(trichloromethyl)-۱H-benzo[d]imidazoleis reported as follows. Affordable starting materials, simple work-up method, short reaction time process and relatively high yields were the advantages of this modified version of Ullmann reaction.

کلیدواژه ها:

Ullmann Reaction ، Trichloroacetonitrile ، Copper-Catalyzed ، Ultrasound Irradiation ، ۱H-Benzo[d]imidazole