nitine Acyltransferases And Their Influence On Coa Pools In Health And Disease

The present text delves into the significance of Coenzyme A (CoA) in cellular metabolism and highlights the importance of regulating concentrations of CoA esters. It explores the carnitine system as a means to maintain CoA reserves and facilitate the transfer of acyl moieties within cells. The passage describes the location, characteristics, and insufficiencies associated with carnitine acyltransferases, underscoring their impact on both CoA pools and metabolic processes. Additionally, it points out the therapeutic benefits offered by specific forms of carnitine in addressing cognitive, cardiac, and metabolic disorders. In order to shed light on how these elements govern acylCoA-dependent reactions within cells, this composition closely examines the intricate workings of the carnitine system which involve multiple proteins connecting intracellular acyl-CoA pools.

کلیدواژه ها:

Coenzyme A ، cellular metabolism ، fatty acid oxidation ، amino acid metabolism ، citric acid cycle ، carnitine acyltransferases ، energy production ، L-carnitine supplementation