Intravenous Iron Sucrose versus Oral Ferrous Fumarate for Treatment of Anemia in Pregnant

Background and Aims:The aim of the current study was comparison of the effectiveness of intravenous iron sucrose versus oral ferrous fumarate for the treatment of iron deficiency anemia during pregnancy. Material and Method: This is a prospective randomized clinical trial enrolling ۱۰۰ pregnant women with iron deficiency anemia who visited the Al-diwaniya Educational Hospital for maternity and children from October ۲۰۲۲ to July ۲۰۲۳ whose ferritin level was less than ۱۵ ng/ml and Hb level was between ۷۰-۱۰.۹g/L. They were treated with either intravenous iron sucrose or oral ferrous fumarate for four weeks.  Formerly, patients were allocated into two groups. The patients in the group I received ferrous fumarate pills, each enclosed with elemental Iron ۱۰۰ mg.  Group II got ۱۰۰ ml of ۰.۹% NaCl containing a dose of iron sucrose dissolved in it and calculated by a specific equation. After four weeks, serum ferritin and hemoglobin levels were assessed, and the adverse effects were also monitored. Results: Comparing hemoglobin levels produces a substantial pre- and post-treatment difference (P=۰.۰۰۱). Serum Ferritin Level harvest significant differences pre- and post-treatment (P=۰.۰۰۱). The post-treatment comparison of the two groups showed a significant difference in each group (P= ۰.۰۰۱).  Conclusion: Maternal iron reserves are more effectively increased by intravenous ferrous sucrose than by oral ferrous fumarate.

کلیدواژه ها:

hemoglobin ، Serum ferritin ، Oral Iron ، Intravenous Iron