Effect of Multichannel Transcranial Direct Stimulation on Global Recovery in Stroke Survivors

Objectives: This study was done to find the effect of multichannel transcranial direct current stimulation (M-tDCS) on motor and cognitive outcomes in individuals with subacute survivors by modulating the cortex of cognitive and motor functions simultaneously.  Methods: This is a two-group, randomized control trial conducted on ۴۰-۷۵-year-old stroke individuals. A total of ۱۴ participants were recruited from outpatient clinics in Punjab, India. Random allocation of participants was done in both groups with n=۷ in each group. The experimental group received M-tDCS. Paretic hand training was done using SaeboFlex and standard physiotherapy rehabilitation. Group B participants received similar treatment except for the sham M-tDCS. The primary outcome measures focused on the assessment of hand function upper extremity function and cognitive domains. Secondary outcome measures focused specifically on the assessment of hand function, including grip strength, pinch strength, and dexterity functions along with the assessment of quality of life assessment and adverse effects associated with the application of transcranial direct current stimulation (tDCS). Statistical analysis was done after four weeks using SPSS software, version ۲۲ by a statistician. One-way ANOVA and independent t-test were used to compute within-group and between-group results at ۹۵% CI and P<۰.۰۵.  Results: Comparison of the changes in scores between the experimental and control groups revealed significant findings for the nine-hole peg test and grip strength whereas non-significant findings for the rest of the outcome measures (P>۰.۰۵).

کلیدواژه ها:

tDCS stimulation ، Stroke Rehabilitation ، Motor recovery ، Non invasive brain stimulation ، neurorehabilitation