CuO nanoparticles: An effective heterogeneous nanocatalyst for the one-pot synthesis of highly substituted pyrroles with pharmacological properties

A convenient one-pot four-component reaction of aromatic aldehydes, β-keto esters and nitromethane in the presence an amine and 10 mol % CuO nanoparticles for the synthesis of highly substituted pyrroles is described. Excellent yields, easily available and less expensive catalyst and easy work-up are the key features of the present method

کلیدواژه ها:

Nano copper oxide ، Highly substituted pyrroles ، Multicomponent reactions ، Nanocatalyst