Determination of antibiotic sensitivity by E-test in resistant Enterococcus species isolated from patients admitted in Khatam- Ol – Anbiya Hospital, Tehran, Iran, , ۲۰۱۳-۲۰۱۵

Enterococcus is the second cause of urinary tract infections in hospitals and the third most common cause of nosocomial bacteremia. Overuse of antibiotics for the treatment of nosocomial infections, causes antibiotic resistance in enterococci resistant to antibiotics through their ability to acquire resistance to antibiotics through mutation or acquisition of genetic material carrying a resistance gene by conjugation or other methods. This cross-sectional study, studied all of the patients admitted in the Khatam – Ol- Anbiya hospital wards during ۲۰۱۳-۲۰۱۵ that ۶۰ cases of patients with nosocomial infections during this period . Demographic data collected from medical records. Samples collected and were sent to the microbiology laboratory. In order to investigate drug-resistant Enterococcusو Antibiogram test by E-Test method were performed. Relevant descriptive variables were analyzed in SPSS software version ۲۱ . ۳۴ (۵۶/۷%) of patients were male. The patient age mean was ۷۰/۷۱+ ۱۸/۳۹ years. Age group ۷۰-۹۰ years, with ۱۷ (۲۷.۹ %) were the most frequent nosocomial infections. Enterococcus dominant species in these patients was ۴۵ (۷۵%) Enterococcus faecalis. Antibiogram E-Test results showed that ۹ cases (۱۸.۳%) were resistance to linezolid, ۲۲ (۳۶/۷ %) resistance to imipenem, ۱۵ (۲۵ %) resistance to meropenem, ۶ patients (۱۰% ) resistance to teicoplanin, ۹ (۱۵%) were resistant to vancomycin.Identification of common antibiotic resistance in every region has great importance and in addition prevents treatment failure. The result of these studies shows that, antibiotic-resistance patterns have changed, and vancomycin resistance, especially among E. faecium, is rising because of nosocomial infections

کلیدواژه ها:

antibiotic sensitivity ، Enterococcus ، E-test ، Microbial Sensitivity Tests ، linezolid