The Effect of an ۸-Week Concurrent Training on Plasma Endothelin_۱ Level and Blood Pressure of Old Women

Background & Aims: Endothelin_۱ secreted by endothelial cells has been identified as the strongest vascular constrictor. The aim of the present study was to investigate the role of concurrent training on plasma concentration of endothelin_۱ and its relationship with blood pressure of old women. Methods: A total of ۲۰ menopause women (Mean age: ۶۷.۴۷±۵.۹۲ years, mean body length: ۱۵۲.۹۲±۷.۵۲cm, mean weight: ۶۵.۸۳±۱۱.۸۳ kg, mean BMI ۲۸.۴۷±۴.۹۸ kg/m۲ , fat percentage: ۱۸.۶۱±۳.۵۷, and WHR: ۰.۹۲۹±۰.۰۴۵) were selected purposefully and randomly assigned into the two groups of ten people. The experimental group did eight weeks of concurrent training in the form of three days per week each day two sessions resistance training with the intensity of ۴۰ to ۶۵% of one maximum repetition and with overload of ۵% after each ۶ sessions and aerobic training with ۶۰ to ۷۰% of maximum heart rate. Before and after eight weeks of exercise, the resting level of endothelin_۱ and systolic and diastolic blood pressure were measured and recorded. Paired t-test was used for investigating the within group changes and independent t-test was used for investigating the between groups differences. Pearson correlation coefficient was used for investigating the relationship between endothelin_۱ concentration and blood pressure. P<۰.۰۵ was considered as statistically significant level. Results: The results of this study showed that an ۸-week concurrent exercise has a significant effect on decreasing endothelin_۱ concentration (p=۰.۰۰۳), and also decreasing systolic (p=۰.۰۰۲) and diastolic (p=۰.۰۰۰) blood pressure of old women. There was a direct correlation between endothelin_۱ level and systolic blood pressure (p=۰.۶۰۱). Nevertheless, there was no correlation between endothelin_۱ level and diastolic blood pressure (r=۰.۳۵۲). Conclusion: Concerning the decrease of plasma endothelin_۱ concentration and decrease of systolic and diastolic blood pressure following concurrent exercise, and concerning the relationship of endothelin_۱ level and systolic blood pressure, it seems that one period of concurrent exercise with this intensity and volume can effect plasma endothelin_۱ concentration as a risk factor for hypertension in old women.

کلیدواژه ها:

Endothelin_۱ ، Hypertension ، Concurrent training