Isolation of Sphingomonas paucimobilis from an ocular infection and identification using ribosomal RNA gene: First case report from Iran

BACKGROUND AND OBJECTIVESThis study reports a case of ocular infection caused by Sphingomonas paucimobilis, diagnosis, and its treatment using different antibiotics.CASE REPORT:A middle-aged woman with prolonged purulent eye discharge was admitted to an ophthalmology clinic. A strain of S. paucimobilis was isolated from a patient who had been admitted to an ophthalmology clinic in Qazvin, Iran. The sample was identified by Sanger sequencing for the ۱۶srRNA gene, and an antibiogram test was performed to determine its resistance profile. The patient was treated with ceftazidime and levofloxacin eye drops. The bacterial culture was negative ۱۸ days after starting treatment with ceftazidime and levofloxacin. Antibiogram results showed that the isolated bacterium was resistant to aminoglycosides and colistin.CONCLUSIONThe study highlights that S. paucimobilis can cause diseases even in immunocompetent individuals. Due to the different resistance profiles that this bacterium may have, treatment should be based on antibiogram results.

کلیدواژه ها:

Sphingomonas Paucimobilis ، Ocular Infection ، ۱۶srrna Sequencing ، Antibiotic Resistance ، Case Report