Frequency of Seropositive Cases of Brucella among Suspected Patients in Sari, during ۲۰۲۱-۲۰۲۳

BACKGROUND AND OBJECTIVESBrucellosis is a bacterial disease that is endemic in Iran due to extensive animal husbandry, especially in Mazandaran. If the disease left untreated, it advances to the chronic phase with complications such as osteomyelitis, bone pain, and jaundice. Laboratory diagnosis of brucellosis is often accomplished by serologic testing. The aim of this study was to investigate seropositivity of Brucella in suspected patients, referred to the laboratory, in Sari.MATERIALS AND METHODSIn a cross-sectional study, blood samples were collected from ۱۶۳۳ suspected brucellosis individuals who were referred to the laboratory. Wright, ۲-Mercaptoethanol (۲-ME), and Coombs-Wright tests were conducted for them. People who had an antibody titer in Wright or Coombs-Wright test higher than ۱:۱۶۰ or ۲-ME more than ۱:۸۰; were considered seropositive. Individuals were categorized based on age and gender.RESULTS AND DISCUSSIONIn this study, ۱۱۲۵ people (۶۸.۹%) were female. ۴۸ people (۲.۹۴%) were seropositive. The average age of seropositive individuals was ۴۹.۸ ± ۱۷.۲ years. there was not a significant relationship between the seropositivity and gender, (females: ۲.۶۷%, males: ۳.۵۴%), but in the range between ۳۰ to ۳۹ years the correlation was significant (females: ۱.۱۰%, males: ۶.۵۴%). ۳۰ seropositive individuals (۶۲.۵%) were referred to the laboratory in the first half of the year.CONCLUSIONAccording to the results obtained from this study, brucellosis is still an important public health problem in Iran. Middle age Males are more susceptible to brucellosis and the probability of contracting the disease increases in the first half of the year.

کلیدواژه ها:

Brucellosis ، Prevalence ، Serological diagnosis