A review of the antibacterial and antiparasitic effects of Matricaria chamomilla L. on infectious diseases

Data about M. chamomilla were gathered using scientific search engines including Web of Science, PubMed, Wiley Online, SpringerLink, ScienceDirect, Scopus, and Google Scholar.Herbal remedies offer accessibility, cultural factors, individual preferences, natural and organic products, and synergistic effects for centuries-old treatmentM. chamomilla, more often known as chamomile, is a well-known medicinal plant that belongs to the Asteraceae family. It is an annual plant that thrives in a variety of soil types and can withstand cold conditions. It is widely used in conventional medicine to treat a wide range of diseases, including infectionsIt is used as an infusion against several infectious diseases, such as female genital infections, infections of the mouth, and eye infections. Externally, the drug in powder form may be applied to wounds slow to heal, skin eruptions, and infections, such as shingles and boils, as well as haemorrhoids.The delicatest strain was Staphylococcus aureus, while the most resistant one was Pseudomonas aeruginosa. The strain that was most vulnerable was Staphylococcus aureus, whereas the strain that was most resistant was Pseudomonas aeruginosa. Gram-negative bacteria may be more vulnerable to M. chamomilla essential oil (EO) than Gram-positive ones are.methanol and various M. chamomilla extracts, such as the alcoholic and ethanolic extracts. Aqueous extracts have demonstrated antibacterial effects against diverse bacterial strains, while extracts and essential oils have demonstrated antibacterial characteristics.The antibacterial effects induced by M. chamomilla extracts and essential oils are likely a result of multiple mechanisms, including membrane disruption, inhibition of essential enzymes, and interference with bacterial adhesion and biofilm formation.Essential oils and extracts from M. chamomilla have been demonstrated in studies to suppress the development of insects and parasites. Leishmania amazonensis and Leishmania infantum exhibited good activity in in vitro tests, and bisabolol activated programmed cell death effects. The combination of M. chamomilla and Foeniculum vulgare hexane extracts had larvicidal efficacy against Culex pipiens, while the methanolic extract showed significant anti-acanthamoeba activity.Therefore, the use of the mentioned plant is due to its antibacterial and anti-parasitic properties, it also has antioxidant, antifungal, and anti-inflammatory properties, which has highlighted the plant as a suitable candidate either individually or in combination with other drugs.

کلیدواژه ها:

Antibacterial and Antiparasitic Effects ، Matricaria Chamomilla L.