Investigation of the antibacterial properties of Malva plant against standard and resistant hospital isolates of Staphylococcus aureus and Klebsiella pneumoniae

BACKGROUND AND ABJECTIVEThe emergence of microbial resistance seems inevitable with almost any new drug. Although antimicrobial resistance is a natural process, it is often the result of inappropriate use of drugs and treatment of infections. Natural extracts, such as plant extracts, have shown significant progress in the discovery of new antimicrobial compounds. The aim of this study is to investigate the antimicrobial effects of Malva extract against MDR and standard Staphylococcus aureus and Klebsiella pneumoniae bacteria.MATERIALS AND METHODSThe alcoholic extract of the Malva plant was followed by MIC and MBC tests against two MDR and standard isolates of Klebsiella pneumoniae and Staphylococcus aureus.RESULTS AND DISCUSSIONThe minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) for standard Staphylococcus aureus were ۳ mg⁄ml and ۱ mg⁄ml for Klebsiella pneumoniae, respectively. The MIC and MBC were ۲ mg⁄ml and ۱ mg⁄ml for MDR Staphylococcus aureus and ۱ mg⁄ml for MDR Klebsiella pneumoniae, respectively.CONCLUSIONPlant extracts with antimicrobial compounds can be used to destroy bacteria that are resistant to all types of antibiotics, significantly reducing the prevalence of antibiotic resistance.

کلیدواژه ها:

Antibacterial ، Malava ، Staphylococcus aureus ، Klebsiella pneumoniae