Hip Infection Caused by Non-typhoidal Salmonella in a Patient with Acute Lymphocytic Leukemia: A case report

BACKGROUND AND OBJECTIVESNon-typhoidal salmonella can cause infections such as gastroenteritis, enteric fever and bacteremia. But hip infection caused by this microorganism is rare.MATERIALS AND METHODSAn ۱۱-year-old girl presented at Shariati hospital's orthopedic department with diagnosis of avascular necrosis (AVN) of the femoral head. Patient also had a history of acute lymphocytic leukemia (ALL). As a part of treatment procedure, surgery was performed. But after that, there was secretions at the site of surgery. Therefore, specimen of patient was sent to the microbiology laboratory and simultaneously antibiotic therapy with meropenem and vancomycin was administered. The levels of C-reactive protein and ESR were elevated. In microbiology laboratory, biochemical tests was conducted and according that the isolated bacteria was citrate positive, urease negative, H۲S positive, indole negative, motility positive, lysine decarboxylase positive, ornithine decarboxylase positive, ortho-Nitrophenyl-β-galactoside (ONPG) negative, methyl-red positive and had an alkaline/acid (K/A) reaction on triple sugar iron agar (TSI). Parallel to these tests, serogrouping test was done and was concordance with biochemical tests. Also, Kirby Bauer disc diffusion test was performed and bacteria was susceptible to cotrimoxazole and ampicillin. For confirmatory diagnosis isolated colony was submitted to VITEK® ۲ (bioMérieux, Marcy L′Ètoile, France). The output result was non-typhoidal Salmonella. After successful treatment the patient was discharged from hospital.CONCLUSIONOur case report study indicated that non-typhoidal salmonella can be isolated from hip infection, so the laboratory technicians must be alert and consider possible present of these bacteria in such infections.

کلیدواژه ها:

Salmonella ، Hip infection ، VITEK