The use of anti-Helicobacter effects of herbal compounds to deal with drug resistance

Helicobacter pylori a spiral bacterium, colonizes in the gastric mucosa of approximately half of the world's population. Its prevalence is different in human and animal species and different geographies and it can be involved in the pathogenesis of gastric ulcer syndrome. The standard treatment of peptic ulcer syndrome includes proton pump inhibitors, bismuth salts, H۲ blockers and antibiotics especially to fight H. pylori. Numerous pharmacological studies have been done to eradicate Helicobacter spp and there are some major problems in this way. It includes high cost, high global prevalence and resistance to available antibiotics. Therefore, replacing new strategies to prevent or manage Helicobacter spp has opened the way to find a natural, accessible and less harmful solution to deal with Helicobacter. According to the reviews and research conducted in scientific sources such as Google Scholar, Scopus and WOS, a number of plants that were sometimes consumed traditionally had significant effects on preventing the growth of this bacteria and healing ulcers and inflammation in the stomach, including canarium album, Syzygium aromaticum, perfume guava, Cuminum cyminum, Pimpinella anisum, Carum carvi, Glycyrrhiza aspera, juglans regia, Ligustrum vulgare, Thymus kotschyanus, Trachy- spermum copticum, Xanthium brasilicum, chaaemelum nobil, cerastium candidissimum, origanum majorana, stachys betonica, fagopyrum esculentum, Moringa oleifera, green tea, zinjiber officinale, curcuma longa, achillea millefolium and aloe vera. The antibacterial effects of some of these plants were comparable to common antibiotics used in the treatment of peptic ulcers, so these plants can be used to produce complementary or even alternative drugs to deal with Helicobacter pylori.

کلیدواژه ها:

Glanders ، Burkholderia mallei ، melioidosis ، horse