Investigating the antibacterial effect of Ajwain plant extract on Aggregatibacter actinomycetemcomitans bacteria

BACKGROUND AND OBJECTIVESPeriodontitis is an infectious disease of the tooth - supporting tissue, caused by several microorganisms that make gradual damage to the periodontal Ligament and alveolar bone by creating an envelope, recession, or both. One of the main causes of periodontal disease is Aggregatibacter actinomycetemcomitans. Ajwain is a plant with many known properties, including antibacterial. Therefore, the present study was performed to determine the antibacterial effect of this aqueous and alcoholic extract of Ajwain on A.a bacteria.MATERIALS AND METHODSIn this experimental study, the diameter of the growth inhibition zone of aqueous - alcoholic extract of Ajwain on Aa was measured by well plate method on ۶ plates and ۲۴ wells with positive and negative control (chlorhexidine ۰.۲ % and solvent). Finally, the information was entered into Spss software version ۲۲ (a = ۰.۰۵).RESULTS AND DISCUSSIONThe results of the present study showed that the mean diameter of growth inhibition zone for ۰.۲ % chlorhexidine mouthwash was, Ajwan extract with concentrations of ۳۰۰ mg/ ml and ۱۵۰ mg / ml and empty solvent respectively ۴۲.۶۶, ۲۲.۵, ۱۶.۳۳ And zero millimeters. Chlorhexidine mouthwash has been shown to have a significantly more growth inhibition zone than two concentrations of Ajwan extract.CONCLUSIONThe present study showed that the extract of Ajwain plant has an Antibacterial effect Against A.a and with more extensive studies, this substance may be used in the treatment of periodontitis and other diseases related to A.a.

کلیدواژه ها:

Ajwain ، Antibacterial ، Aggregatibacter actinomycetemcomitans