The role of the microbiota in the process of cancer and the future of treatment

BACKGROUND AND OBJECTIVESIn spite of decades of clinical research, Cancer has become one of the most important health problems for humans .Here we review the status of effects of microbiota on the healing process and cancer treatment .The purpose of this review is cancer treatment and reduction of side effects.MATERIALS AND METHODSAn organized review was completed on original research extracted from PubMed and Google scholar. We searched with the keywords which is mentioned below.RESULTS AND DISCUSSIONBy reviewing the data, we came to the conclusion that microbiota metabolites can have an effect on cancer progression and modulate it, and have fewer side effects than radiotherapy.Also, using microbial metabolites in chemotherapy will reduce the severe side effects caused by the treatment and will lead the treatment in a better direction.CONCLUSIONThe results of present study showed there is possibility that Microbiota has a bright future in cancer treatment, and maybe in the future it can be used as an alternative to radiotherapy and chemotherapy.

کلیدواژه ها:

Cancer Therapy ، Gut Microbiota ، Chemotherapy ، Immune System