Evaluation of the Relationship Between Short Femur Length and Preeclampsia

Background and Objective:  Preeclampsia is a disorder of pregnancy with increased maternal and perinatal morbidity and mortality. The detection of a short femur length, particularly below the ۵th centile is often a diagnostic dilemma. It might be associated with fetal growth restriction at the time of the ultrasound examination The purpose of this study was to assess the contribution of short femur diaphysis length (FDL) at ۳۲–۳۷ weeks of gestation in preeclampsia.Material and Methods: The study included pregnant women who underwent a routine anomaly scan at ۳۲–۳۷ weeks of gestation at the Shahid Motahari University Hospital (Iran, Urmia) between February ۲۰۲۱ and February ۲۰۲۲. Fetal biometry and Doppler ultrasound of uterine arteries were assessed as part of the anomaly scan, and the mean pulsatility index of both uterine arteries was recorded. Maternal obstetric characteristics, such as ethnicity, age, weight, parity, cigarette smoking, and medical history including hypertension and diabetes mellitus were collected from our database system.Results: the results of the present study illustrated that multivariate analysis of fetal femoral length percentile was associated with maternal age, preeclampsia, and the number of previous pregnancies. Furthermore, the sensitivity and specificity of the ۵۰th-percentile femoral in the diagnosis of preeclampsia were % ۹۶.۸۸ and %۸۱.۸۸  respectively. Conclusions: our results suggest that Short FDL at ۳۲–۳۷ weeks of gestation is a significant relationship with PE.

کلیدواژه ها:

biomarker ، Preeclampsia ، femur length ، complications of pregnancy