The Impact of G۱۵۷۵A Matrix Metalloprotease-۲ Gene Polymorphism on Male Fertility

Background: Matrix metalloproteinases contain more than ۲۰ enzymes that require zinc for their activities. Gelatinases are one of the subtypes of matrixmetalloproteinases, which degrade gelatin and collagen type ۴, and are present in male reproductive tissues such as in prostate. G۱۵۷۵A Matrix Metalloproteinase-۲ (MMP-۲) gene polymorphism affects MMP-۲ activity.