Outcome of Cardiac Rehabilitation Program on Plasma Adiponectin Levels and Lipid Profile in Patients with Coronary Heart Disease

Background: Cardiac rehabilitation program (CRP) is a non-pharmacological treatment in patient with coronary heart disease (CHD). The present study was aimed the effect of CRP on adiponectin and lipid profiles in CHD patients during 8 weeks. Materials and Methods: Sixty patients with CHD were divided to 2 groups: the exercise group (EG), who completed a series of CRP (3 times a week, in the morning, at 60-85% of MHR, lasted 45-60 minutes for 8 weeks), and a control group (CG) who did not exercise during 8 weeks. In each group, 16 patients were female and 14 patients were male (n = 30). The body mass index (BMI), waist to hip (WHR), cardiorespiratory variables were determined at baseline after 8-week. Medication and diet remained unchanged in both groups during this period. Data were evaluated by independent t-tests by SPSS software in the significant level P-value < 0.05. Results: The results showed that there was a significant difference in anthropometric and cardiorespiratory variables except in RDBP between two groups after CRP. Also, a significant decrease was observed in the EG group for serum TC, LDL and TG levels, RSBP, body weight, BMI, WHR and a significant increase for FC, HDL and adiponectin levels compared to baseline (P < 0.05). HDL-cholesterol level in exercise group was higher than control group after CRP (P < 0.05). Conclusion: Cardiac rehabilitation based on aerobic exercise training may improve plasma lipid profile and adiponectin level in CHD patients, in the absence of changes in diet or medication.

کلیدواژه های Outcome of Cardiac Rehabilitation Program on Plasma Adiponectin Levels and Lipid Profile in Patients with Coronary Heart Disease:

Coronary heart disease ، Cardiac rehabilitation program ، Adiponectin ، Lipid profile