Outcome of Cardiac Rehabilitation Program on Plasma Adiponectin Levels and Lipid Profile in Patients with Coronary Heart Disease

Background: Cardiac rehabilitation program (CRP) is a non-pharmacological treatment in patient with coronary heart disease (CHD). The present study was aimed the effect of CRP on adiponectin and lipid profiles in CHD patients during ۸ weeks. Materials and Methods: Sixty patients with CHD were divided to ۲ groups: the exercise group (EG), who completed a series of CRP (۳ times a week, in the morning, at ۶۰-۸۵% of MHR, lasted ۴۵-۶۰ minutes for ۸ weeks), and a control group (CG) who did not exercise during ۸ weeks. In each group, ۱۶ patients were female and ۱۴ patients were male (n = ۳۰). The body mass index (BMI), waist to hip (WHR), cardiorespiratory variables were determined at baseline after ۸-week. Medication and diet remained unchanged in both groups during this period. Data were evaluated by independent t-tests by SPSS software in the significant level P-value < ۰.۰۵. Results: The results showed that there was a significant difference in anthropometric and cardiorespiratory variables except in RDBP between two groups after CRP. Also, a significant decrease was observed in the EG group for serum TC, LDL and TG levels, RSBP, body weight, BMI, WHR and a significant increase for FC, HDL and adiponectin levels compared to baseline (P < ۰.۰۵). HDL-cholesterol level in exercise group was higher than control group after CRP (P < ۰.۰۵). Conclusion: Cardiac rehabilitation based on aerobic exercise training may improve plasma lipid profile and adiponectin level in CHD patients, in the absence of changes in diet or medication.

کلیدواژه ها:

Coronary heart disease ، Cardiac rehabilitation program ، Adiponectin ، Lipid profile