Macroscopic Evaluation of the Effect of Low Level Laser and Plasma Jet on Wound Healing in Rats

The aim of this study was to evaluate and compare the macroscopic effect of low level laser and plasma jet for wound healing in rats. The study was performed on ۴۰ old male white rats with an average weight of ۲۵۰ g and an average age of the same age.After preparing the rats from Ibn Sina Research Institute, they were kept the same for one week under environmental conditions such as temperature, humidity and light, and nutrition such as the type of diet and the number of meals. Then, to start the research, rats were randomly divided into two groups (A): laser treatment of wounds, group (B): plasma wound treatment. All rats were inhibited ۴ hours before each anesthesia under conditions of abstinence and up to ۲ hours after drinking water. Rats were anesthetized by intraperitoneal injection of ketamine ۱۰% and xylazine ۲%.After scrubbing between two shoulders of each rat, a circular wound was created by sterile ۵ mm biopsy puncture. Group A rats were treated with low level laser in three sessions (each one ۵-۷ minutes) and group B in three sessions (each one ۲ minutes) with argon plasma. Based on the wound contraction and observed results, it seems that Low level laser radiation has more acceptable and appropriate effects than cold plasma on the healing of rat skin wounds.

کلیدواژه ها:

Wound healing ، Low level laser ، plasma jet