Skin Ulcers Treatment of Breast Cancer with Collagen Superabsorbent Powder Containing Silver Nanoparticles

Background: Breast cancer (BC) with skin ulceration is one of the main causes of cancer-associated deaths in women worldwide that imposes substantial medical and economic burden because often unsuccessful therapeutic methods. At now, Nanotechnology offers potential solutions to selectively target BC cells without causing any impairments to the adjacent normal tissues or organs. Therefore, the aim of the present study was to assay the skin ulcers improvement of BC with nano silver particles.Materials and Methods: In this study, we present the case of a tissue ulceration of left breast of a female patient with breast cancer that underwent nanotherapy (collagen superabsorbent powder containing ۱۵ ppm nano silver particles) at the same time as chemotherapy (Hydrocortisone), and head and neck radiotherapy.Results: Within two months, the wound was almost completely cured and any side effects was not observed during treatment and after ۶ months of follow. At the same time as the wound healed, the supraclavicular and axillary mass gradually also became smaller and the sound in the left lung decreased. So that, after ۸ month the sound of the lungs became normal.Conclusion: We recommend collagen superabsorbent powder containing silver nanoparticles as adjunctive therapy or even alternative treatment in the skin ulcers treatment of Breast cancer. Further studies on greater population are needed to confirm this finding.

کلیدواژه ها:

Breast cancer ، Nanotechnology ، Nano silver particles ، Chemotherapy ، Radiotherapy