Estimation of Photon Specific Absorbed Fractions in Digimouse Voxel Phantom using Monte Carlo Simulation Code FLUKA
محل انتشار: مجله فیزیک و مهندسی پزشکی، دوره: 6، شماره: 4
سال انتشار: 1395
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 57
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شناسه ملی سند علمی:
JR_JBPE-6-4_002
تاریخ نمایه سازی: 30 دی 1402
چکیده مقاله:
Background: Most preclinical studies are carried out on mice. For internal dose assessment of a mouse, specific absorbed fraction (SAF) values play an important role. In most studies, SAF values are estimated using older standard human organ compositions and values for limited source target pairs.Objective: SAF values for monoenergetic photons of energies ۱۵, ۵۰, ۱۰۰, ۵۰۰, ۱۰۰۰ and ۴۰۰۰ keV were evaluated for the Digimouse voxel phantom incorporated in Monte Carlo code FLUKA. The organ sources considered in this study were lungs, skeleton, heart, bladder, testis, stomach, spleen, pancreas, liver, kidney, adrenal, eye and brain. The considered target organs were lungs, skeleton, heart, bladder, testis, stomach, spleen, pancreas, liver, kidney, adrenal and brain. Eye was considered as a target organ only for eye as a source organ. Organ compositions and densities were adopted from International Commission on Radiological Protection (ICRP) publication number ۱۱۰.Results: Evaluated organ masses and SAF values are presented in tabular form. It is observed that SAF values decrease with increasing the source-to-target distance. The SAF value for self-irradiation decreases with increasing photon energy. The SAF values are also found to be dependent on the mass of target in such a way that higher values are obtained for lower masses. The effect of composition is highest in case of target organ lungs where mass and estimated SAF values are found to have larger differences.Conclusion: These SAF values are very important for absorbed dose calculation for various organs of a mouse.
کلیدواژه ها:
نویسندگان
A Sinha
Faculty of Physical Science, Shri Ramswaroop Memorial University, Lucknow
H Patni
Bhabha Atomic Research Center, Mumbai- ۴۰۰۰۸۵
B Dixit
Faculty of Physical Sciences, Shri Ramswaroop Memorial University, Lucknow- ۲۲۵۰۰۳
N Painuly
Department of Radiotherapy, King George Medical University, Lucknow-۲۲۶۰۰۳
N Singh
Department of Radiotherapy, King George Medical University, Lucknow-۲۲۶۰۰۳