Antibiotic resistance / susceptibility of ۳۰ isolates of Bacillus anthracis isolated in Iran between ۲۰۰۷ and ۲۰۰۸

Thirty isolates of Bacillus anthracis recovered from animal carcasses, soil and human in different localities in Iran between ۲۰۰۷ and ۲۰۰۸. They were tested by standard disc diffusion susceptibility method for their resistant/ susceptibility to different kinds of antibiotics. According to American National Committee of Clinical Laboratory Standards (NCCLS) guidelines all isolates were sensitive to levofloxacin (۱۰۰%), cefixime (۱۰۰%). Other isolates showed different kinds of sensitivity to: doxycycline (۹۶.۷%), cephalothin (۹۵.۶%), ampicillin (۹۵.۶%), nitrofurantoin (۹۵.۶%), tetracycline (۹۴.۴%), ofloxacin (۸۹.۹%), gentamycin (۷۷.۸%), nalidixic acid (۷۲.۲%), kanamycin (۷۵.۶%), erythromycin (۷۱.۱%), piperacillin (۷۸.۹%), tobramycin(۶۴.۴%), choramphenicol (۵۹.۹%), cefotaxime (۳۳.۳%), ciprofloxacin (۱.۱%), cefuroxime (۳۳.۳%), azithromycin (۴۴.۴%), streptomycin (۵۵.۶%), ticacillin (۳۵.۶%), rifampicin (۳۴.۴%), clindamycin (۷۴.۴%), ceftriaxon (۲۶.۷%), methicillin (۵۵.۶%), trimethoprim (۸.۹%), cloxacillin (۳۱.۱%) and penicillin (۷۴.۴%). One of the isolates was complete resistance to penicillin.Therefore, preventive and therapeutic strategies involving the use of antibiotics should take the possibility of resistance and/or susceptibility of the isolates into account and not decided without antibiotic sensitivity testing.

کلیدواژه ها:

Bacillus anthracis ، Antibiotics ، Resistance/susceptibility ، Iran