Comparison of the effect of vaginal capsule of evening primrose oil and misoprostol on cervical ripening of nulliparous women with post-term pregnancy: A clinical Trial

The rates of perinatal mortality and neonatal morbidity are higher for post-termpregnancies than for term pregnancies. The present study was conducted tocompare the effect of vaginal capsule of evening primrose oil and misoprostol oncervical ripening of nulliparous women with post-term pregnancy. This one-blindrandomized trial conducted on ۱۳۰ pregnant women with post-term pregnancyvisiting to the labor ward of Sanandaj Besat Hospital. Samples were divided intotwo groups of intervention and control with the randomized allocation method.The intervention group received ۵۰۰ mg vaginal evening primrose capsule and ۲۵micrograms of sublingual misoprostol and the control group received a placebovaginalcapsule and ۲۵ micrograms of misoprostol sublingually. Data collectingtools include: demographic spesifications questionnaire and Bishop Checklist.Data was analyzed by SPSS software version ۱۵ and by using Chi-square T-testone-way ANOVA test. The results showed that the mean bishop scores of thesubjects in the intervention group were significantly higher than the controlgroup (p <۰.۰۵). There was no significant difference in uterine contractionsfetal heart rate and vital signs between two groups (p> ۰.۰۵). The results ofthe present study showed that vaginal capsule of evening primrose oil withmisoprostol on the cervical ripening in post-term pregnancies was more effectivethan misoprostol alone."Vaginal evening primrose oil Misoprostol Cervical ripening Post-term pregnancyBishop score"