The Effect of Eight Weeks of Concurrent Training on Serum Levels of Paraxonase-۱, Irisin, Lipid Profile, and Insulin Resistance in Men With Metabolic Syndrome
محل انتشار: فصلنامه پزشکی هرمزگان، دوره: 27، شماره: 1
سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 90
فایل این مقاله در 7 صفحه با فرمت PDF قابل دریافت می باشد
- صدور گواهی نمایه سازی
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_HMJ-27-1_009
تاریخ نمایه سازی: 14 آذر 1402
چکیده مقاله:
Background: Irisin is a myokine suggested to exert anti-obesity benefits. On the other hand, paraxonase-۱ (PON ۱) is one of the most important free radical scavenging enzymes and is among the main protectors of lipoproteins against oxidizing compounds. This study aimed to evaluate the effect of ۸ weeks of concurrent training on serum levels of irisin, PON ۱, lipid profile, and insulin resistance in men with metabolic syndrome.
Methods: In this quasi-experimental study, ۳۰ men with metabolic syndrome (aged ۲۵-۳۵ years and with body mass > ۲۵ kg.m-۲) were purposefully selected and randomly divided into two groups of concurrent training (n = ۱۵) and control (n = ۱۵). Three sessions of the training program were held per week over an ۸-week interval. Concurrent training included warm-up, resistance (۲۰ minutes of resistance training), and endurance (۲۵ minutes of activity on a stationary bike with an intensity of ۵۰%-۸۰% of maximum heart rate). Blood samples were collected before and ۲۴ hours after exercise to measure serum levels of variables. Data were analyzed using independent and dependent t-tests.
Results: At baseline, serum levels of PON ۱, irisin, and high-density lipoprotein (HDL) were higher in the concurrent training group. The results of the study also indicated that ۸ weeks of concurrent training significantly reduced the levels of insulin resistance, triglycerides (TG), cholesterol, low-density lipoprotein (LDL), systolic, and diastolic blood pressure in men with metabolic syndrome.
Conclusion: Eight weeks of concurrent training improves the levels of irisin, insulin resistance, PON ۱, and lipid profile of men with metabolic syndrome.
کلیدواژه ها:
نویسندگان
Seyed Amir Hosain Diba Hosaini
Department of Sport Physiology, Mahallat Branch, Islamic Azad University, Mahallat, Iran
Morvarid Vafaee
Department of sport physiology, Olomtahghighat Branch, Islamic Azad University, Tehran, Iran
Bahram Abedi
Department of Sport Physiology, Mahallat Branch, Islamic Azad University, Mahallat, Iran