Prevalence of Adverse Transfusion Reactions in Hospitalized Patients in Tertiary Heart Center of Sari, Iran in ۲۰۱۴-۲۰۲۰

Introduction: Our study aimed to determine the prevalence of adverse transfusion reactions (ATRs), unexpected or undesirable effects resulting from the therapeutic use of blood products. Material and Methods: In this cross-sectional study, we assessed the medical records of ATR patients who were referred to Mazandaran Heart Center from March ۲۰۱۴ until July ۲۰۲۰. Patients needed blood transfusions during the operation for various reasons; complications related to blood administration were considered ATR. Age, sex, associated clinical signs, symptoms, and adverse response were composed of a patient's file checklist with ethical points. SPSS ۱۶.۰ was used for statistical analysis. Results: In this study, ۲۳,۲۰۶ blood products were used in hospitals as treatment, and there were ۹۶ reactions (۴%) because of transfusion, and ۱۰ patients had a history of recent reactions. There was not any specific connection between the age of patients and the existence of complications. Most reactions were allergic (۴۴%) and non-hemolytic febrile reactions (۴۲%). It is essential to state that ۹۱% of adverse reactions were slight ones, and only ۵% led to the injury. Out of ۹۶ patients with complications, ۷۹ patients received blood products as pack cells; ۶ patients received Fresh Frozen Plasma; ۳ patients received autologous blood products, while this number was one for Blood Low Leukocytes and platelets (PLT). Conclusion: Based on this investigation, the risk of adverse transfusion reactions (ATRs) is ۴%, and universally ۸۵ million units of blood products are transfused every year. Consequently, investigation to reduce this number is required.

کلیدواژه ها:

Adverse transfusion reaction ، Autologous ، Blood transfusion