Prevalence of vulvovaginal candidiasis in gynecological practices in Germany: A retrospective study of ۹۵۴,۱۸۶ patients

Background and Purpose: To the best of our knowledge, no information is available regarding the treatment of vulvovaginal candidiasis in gynecological practices. The goal of this study was to analyze the prevalence of vulvovaginal candidiasis (VVC) and the drugs prescribed for the treatment of this condition in women followed in gynecological practices in Germany. Materials and Methods: All the women followed in ۲۶۲ gynecological practices between November ۲۰۱۴ and October ۲۰۱۶ were included in this study. The first outcome was the prevalence of patients diagnosed with VVC during this period. The second outcome was the prevalence of women with VVC who received an appropriate vaginal or systemic antimycotic prescription within ۳۰ days after their first VVC diagnosis. Covariables included the use of gynecological/systemic antibiotics, consumption of oral/vaginal contraceptives, cancer, pregnancy, diabetes, and psychiatric diseases including depression, anxiety, and adjustment and somatoform disorders. Results: Between ۲۰۱۴ and ۲۰۱۶, ۹۵۴,۱۸۶ women were followed in gynecological practices, and ۵۰,۲۷۹ (۵.۳%) women were diagnosed with VVC during the same period. The use of gynecological antibiotics (OR=۲.۸۸), systemic antibiotics (OR=۱.۴۵), oral contraceptives (OR=۱.۷۴), and vaginal contraceptives (OR=۱.۸۴) were associated with an increase in the risk of VVC diagnosis. Cancer (OR=۱.۲۰) and pregnancy (OR=۱.۵۹) were additional risk factors. Approximately ۷۵% of women diagnosed with VVC received an antimycotic prescription. The three most frequently prescribed drugs were clotrimazole (۷۲%), fluconazole (۱۴%), and nystatin (۶%). Conclusion: More than ۵% of women were diagnosed with VVC and the majority of them received an appropriate prescription.

کلیدواژه ها:

Germany ، Gynecological practices ، Prescription ، Prevalence ، Vulvovaginal candidiasis