Ataxia-telangiectasia With Acute Rheumatic Fever: A Case Report

Background: Ataxia-telangiectasia is a multi-organ disease. It is due to a mutation of the Exon No. ۵ ataxia telangiectasia mutated gene (c.۳۸۱delA: p.v۱۲۸fls). Complications including recurrent infections, progressive cerebellar ataxia, and varying degrees of humoral and cellular immunodeficiency arise.  Case Presentation: We report a ۷-year-old girl patient with A-T who developed acute rheumatic fever.  Conclusion: Rheumatoid disorders and or infectious diseases such as acute rheumatic fever could be observed in A-T patient.

کلیدواژه ها:

Ataxia-telangiectasia ، Mutation ، Immunocompromised patient ، Acute rheumatic fever