Phytochemicals and Biological Activities of Froriepia subpinnata (Ledeb.) Baill. Extracts

Nowadays, the use of herbal extracts for preparing various drugs is increasing because of the compatibility of the natural compounds present in the extracts with the human body. To this end, in this project, we studied Froriepia subpinnata (Ledeb.) Baill. in terms of its natural constituents and biological activities. The chemical composition of the hexane extract of F. subpinnata aerial parts was evaluated by the GC/MS analysis and ۲۱ compounds (۸۰.۶۰%) of the total, including phytosterols and hydrocarbons, were identified. Also besides, a significant amount of flavonoids in the methanol extract of F. subpinnata (۲۷.۲۳۵ ± ۰.۰۴۸μg/mL) was estimated by the AlCl۳ colorimetric method. Two flavonoids: rutin and catechin were identified in the methanol extract of F. subpinnata by HPLC analysis. The concentration of the flavonoids was evaluated (۲۳.۶۱ and ۶.۹۵) mg/g respectively. Antioxidant activity of the methanol extract of the species was also evaluated by the DPPH (۱,۱-diphenyl-۲-picryl-hydrazyl) assay. We also investigated the antibacterial activity of methanol extract of F. subpinnata aerial parts against two bacteria Staphylococcus aureus and Escherichia coli by the MIC (Minimum Inhibition Concentration) method. The MIC values for S. aureus and E. coli were evaluated (۰.۰۳۱ and ۱.۰) mg/mL respectively. Our study shows that F. subpinnata possesses a variety of useful natural constituents, which makes it a promising plant for agricultural and medicinal uses.

کلیدواژه ها:

Froriepia subpinnata ، phytosterol ، rutin ، Antioxidant ، Staphylococcus aureus