Synthesis and characterization of nanocomposite hydrogel based onnanobead chitosan in the presence of Fe۳O۴@SiO۲-Ag nanoparticles and itsuse to study surface absorption of vitamin B۱۲

The use of nanoparticles in drug delivery systems has attracted a lot of attention over the lastfew years. Nanoparticles, which are made up of a mixture of Natural and Synthetic orSemisynthetic polymers, are colloidal particles. This study was conducted with the aim ofdeveloping an efficient catalyst, magnetic nanocomposite Fe۳O۴@SiO۲-Ag, for the surfaceadsorption of vitamin B۱۲ through a one-pot multicomponent reaction. [۱]. Nanoparticles are ofgreat importance because they can transfuse different components at the right time, which isimportant for drug carriers. [۲]. The biodegradable biocompatible polymer chitosan has attractedconsiderable interest in drug delivery. In this study, a Chitosan nanocomposite based hydrogel wasfirst created and then prepared and investigated with Fe۳ o۴ @ SiO۲ Ag magnetic nanoparticlesfor studies of vitamin B۱۲ adsorption. TGA, VSM, XRD, FTIR, TEM and SEM studies werecarried out to determine the method for sample identification[۳].