Comparison Of Pathologic Differences In Adenoid Tissues Of Allergic Patients With Non-Allergic Patients

Background: Tonsils are masses of lymphatic tissue that play a significant role in protecting the body against pathogens and allergens due to their location in the upper respiratory and gastrointestinal tracts. Method: Fifty patients with allergic adenotonsillar hypertrophy and fifty patients with non-allergic adenotonsillar hypertrophy were selected as candidates for surgery by specialist. Obtained samples were sent to the pathology department and then compared in terms of pathology, number of eosinophil, lymphocytes, neutrophils and the presence or absence of lipids by a specialist. Results: That among all the studied variables, family history of asthma and allergic rhinitis, history of asthma and allergic rhinitis in the patient, positive result of prick test (air allergen, food and mite) and lymphocyte count were significantly higher in patients with allergic adenotonsillar hypertrophy than in patients with non-allergic adenotonsillar hypertrophy. Neutrophil count was significantly higher in patients with non-allergic adenotonsillar hypertrophy than in patients with allergic adenotonsillar hypertrophy (P-value <۰.۰۰۱). In other variables such as eosinophil count, presence of lipids, gender, age, family history of tonsillitis, smoking in the family, largeness of pharyngeal tonsils, diagnosis method, apnea, persistent night snoring and continuous mouth breathing, there was no statistically significant difference between the two groups (P-value> ۰.۰۵). Conclusion: The significant difference between clinical and pathologic characteristics of adenoid tissues of allergic patients and non-allergic patients suggest that special attention should be paid for diagnosis and treatment of these patients. However, more comprehensive study with a larger sample size is needed to evaluate this issue more accurately.

کلیدواژه ها:

Tonsil ، Adenotonsillar Hypertrophy ، Allergy ، Eosinophil ، Lymphocyte ، Neutrophil