Behavior and Prognosis of Ovarian Cancer with Rare Metastatic Sites
محل انتشار: مجله سرطان خاورمیانه، دوره: 14، شماره: 3
سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 52
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شناسه ملی سند علمی:
JR_MISJ-14-3_011
تاریخ نمایه سازی: 25 آبان 1402
چکیده مقاله:
Background: Ovarian cancer is the most prevalent gynecologic malignancy in Egypt. Although metastasis from ovarian cancer is common, there are still sites with rarely reported deposits as non-regional nodes, bone, and brain.Method: We retrospectively recruited a group of patients over a ۷-year period from the data system of a cancer center. All the recruited patients suffered from a rare distant metastasis from ovarian cancer. We used statistical software (SPSS) for the analysis of the study results. Continuous variables were presented as mean and standard deviation, if normally distributed, or median and range when non-normally distributed. Independent samples t-test was utilized to compare parametric data, whereas nonparametric data were compared through the use of the Mann-Whitney U test. Categorical data were compared with Pearson's Chi-square test or Fischer-Exact test when appropriate. A P-value < ۰.۰۵ was considered to be statistically significant.Results: Nearly half of the patients already had metastasis at the time of the initial presentation, while the rest developed it during the disease course. Debulking was feasible in nearly half of the patients with long overall and progression-free survival. Tumors with non-regional nodal metastases seemed to have excellent survival.Conclusion: We could recommend offering these patients optimal debulking and considering those with a non-regional nodal spread as having a curable disease.
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نویسندگان
Mohammad Zuhdy
Department of Surgical Oncology, Oncology Centre, Mansoura University (OCMU), Mansoura, Egypt
Reham Alghandour
Medical Oncology Unit, Oncology Centre, Mansoura University (OCMU), Mansoura, Egypt
Omar Hamdy
Department of Surgical Oncology, Oncology Centre, Mansoura University (OCMU), Mansoura, Egypt
Islam Metwally
Medical Oncology Unit, Oncology Centre, Mansoura University (OCMU), Mansoura, Egypt
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