The Effect Of Liberal Hydration Dextrose Saline On Postoperative Nausea And Vomiting (PONV) Following Tonsillectomy In Children ۲-۱۲ Years Old

Background: PONV is one of the most unpleasant complications following surgery. Fluid therapy may be an effective strategy to reduce PONV in children. The aim of this study was to evaluate the effect of ۵% dextrose-۰.۹% saline (DS) solution on nausea and vomiting after tonsillectomy in children aged ۲-۱۲ years old. Method: The present study is a randomized double-blind clinical trial that was performed on children aged ۲ to ۱۲ years. Participants were randomly assigned to the three groups receiving ۳۰ml kg-۱ h-۱ DS solution, ۳۰ml kg-۱ h-۱ Ringer’s lactate (RL), and ۳۰ml kg-۱ h-۱ normal saline ۰.۹% (NS). After transferring the child to the operating room bed, fluid therapy was started. At the end of surgery blood sugar was checked with a glucometer. Also, the number and frequency of each episode of nausea and vomiting were observed and recorded after surgery. Results: ۶۰ children participated. Based on ANOVA results, a statistically significant difference was observed in the blood sugar of the three groups (p-value <۰.۰۰). Tukey's post-hoc test showed that this difference between the DS group and NS and RL groups was significant (p-value <۰.۰۰), No significant difference was observed between the effects of three types of crystalloid solution on PONV. Conclusion: The use of three types of crystalloid solutions could reduce the overall PONV in all three groups. However, no significant difference was observed between the DS solution and other crystalloid solutions, and it caused a significant increase in blood sugar compared with the other two groups.

کلیدواژه ها:

PONV ، Fluid Therapy ، dextrose ، Tonsillectomy.