Evaluation of the Effects of Vitamin C in Prognosis of Patients with Sepsis in Zanjan Vali- e-Asr Hospital in ۲۰۲۰
سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 56
فایل این مقاله در 8 صفحه با فرمت PDF قابل دریافت می باشد
- صدور گواهی نمایه سازی
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_ZUMS-31-147_007
تاریخ نمایه سازی: 10 آبان 1402
چکیده مقاله:
Background and Objective: Regarding the high prevalence of sepsis, it is important to discover methods to control this condition. Valuable effect of vitamin C in vasopressin synthesis is demonstrated, moreover, its antioxidant effect reduces vascular infiltration. Therefore, the beneficial effects of vitamin C in prognosis of the patients who have been admitted to Vali-e- Asr hospital in Zanjan, Iran with the diagnosis of sepsis have been evaluated.
Materials and Methods: This cross sectional study was planned on patients with sepsis who have been admitted to the infectious ward of Vali-e-Asr hospital in Zanjan. Patients with sepsis above ۱۸ years old from June to March ۲۰۲۰ have been included in this study. Data of patients whom have received intravenous vitamin C, ۲۵ mg/kg/۲۴h for ۴ days, and patients without reception vitamin C was collected from their files. Their demographic, clinical and para clinical information were collected, then the information was analyzed.
Results: ۵۴ patients (۲۶ received vitamin C and ۲۸ did not receive vitamin C) were enrolled in this study. Considering that the two groups were matched from the beginning of the study, no statistically significant difference was found between the two groups of patients in demographic characteristics. Furthermore, there were no significant differences in the sepsis induced complications, e.g. laboratory findings, mean days of hospitalization in ICU and SOFA score.
Conclusion: Our findings demonstrated that no clear statistically significant difference was found between the two groups of control and vitamin C received groups; nonetheless for precise conclusion more studies with larger groups are required.
کلیدواژه ها:
نویسندگان
Afsaneh Karami
Dept. of Infectious Diseases, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
Fattaneh Fallahpour
Dept. of Infectious Diseases, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
Nima Motamed
Dept. of Epidemiology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
Mohammad Reza Jafari
Dept. of Pharmacology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
مراجع و منابع این مقاله:
لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :