Multicomponent Solvent-Free Synthesis, Antimicrobial and Antifungal Evaluation of Novel N-Amino Benzylthiolates
محل انتشار: دوفصلنامه تحقیقات شیمی آلی، دوره: 4، شماره: 2
سال انتشار: 1397
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 84
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شناسه ملی سند علمی:
JR_ORGC-4-2_002
تاریخ نمایه سازی: 3 مهر 1402
چکیده مقاله:
Novel N-amino benzylthiolates were synthesized via multicomponent reaction of malononitrile, isothiocyanates and benzyl halides under conventional and solvent-free conditions. Various electron-donating and -withdrawing substitutes within both isothiocyanates and benzyl halides were used to demonstrate the efficiency of new methodology. A broad spectrum of antibacterial and antifungal activities were observed especially within benzyl halides containing electron-withdrawing aryl substituents.
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نویسندگان
Hamid Beyzaei
Department of Chemistry, Faculty of Science, University of Zabol, Zabol, Iran
Hossein Heidari
Department of Chemistry, Faculty of Science, University of Zabol, Zabol, Iran
Reza Aryan
Department of Chemistry, Faculty of Science, University of Zabol, Zabol, Iran