Intelligent Nanoparticle-Based Dressings for Bacterial Wound Infections

سال انتشار: 1401
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 241

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شناسه ملی سند علمی:

WTRMED09_049

تاریخ نمایه سازی: 23 مرداد 1402

چکیده مقاله:

ntroduction: As wound restoration stays a project for the scientific place, wound manipulate has stopped up an essential detail for healthcare systems. Nanoparticles were produced and carried out in a huge fashion of merchandise worldwide, which embody silver nanoparticles(AgNP) and tremendous compounds consisting of nitric oxide and chitosan. Method: In the forthcoming systematic study, the required data were collected using keywords and citing valid databases such as: Scopus PubMed, Google Scholar and ProQuest. The statistical population of the study includes all studies conducted up to ۲۰۲۲ in the field of Intelligent Nanoparticle-Based Dressings for Bacterial Wound Infections. After reviewing the relevant findings and evaluating the data quality, a total of ۳۳ articles were analyzed. Results: Nanoparticles withinside the meantime is taken into consideration a possible opportunity to antibiotics and that they have high ability to resolve the trouble of the emergence of bacterial multidrug resistance. The in vitro of nitric oxide nanoparticles stimulates the migration of fibroblasts and collagen to the wound place. Furthermore, calcium-based totally really nanoparticles raise up pores and skin wound restoration. The microbial invasion breaching the pores and skin’s intact facility end result in do away with restoration. AgNP have the capability to damage germs whilst furthermore selling pores and pores and pores and skin regeneration. The unic assets improves that they can each affectively shop you wound infections and beautify the restoration processin comparison with conventional topical treatments. AgNPs offer a massive surface-place-amount ratio wich may additionally permit nanoparticles to attach to a microbe’s surface, boom its permeability and end result in membrane dissolution. Increased permeability can also permit AgNPs to consequences penetrate a microbe and harm the intracellular organisms. Conclusion: Combining a hydrogel matrix with Ag nanoparticles has fantastic advantages for each wound-restoration and antibacterial purposes. The physical, chemical and biological homes of engineered matrices and AgNP were considerably studied and severa makes use of were defined, however there stay fantastic possibilities to discover AgNP interest from cell to cell in human beings and network in choice to systemic toxicity.

نویسندگان

Raziyeh Hasanvand

Student of Medicine, School of Medicine, Iran University of Medical sciences, Tehran, Iran

Parsa Veysi

Student of Medicine, School of Medicine, Qom Islamic Azad University of Medical sciences, Qom, Iran

Leila Ali Nasab Maleki

Student of Medicine, School of Medicine, Qom Islamic Azad University of Medical sciences, Qom, Iran

Zahra Shahzad

Student of Medicine, School of Medicine, Mashhad Islamic Azad University of Medical sciences, Mashhad, Iran

Setayesh Sadr

Student of Medicine, School of Medicine, Mashhad Islamic Azad University of Medical sciences, Mashhad, Iran

Elaheh Oliyaei

Bachelor student of radiology,Faculty of Paramedicine,Department of medicine, Bushehr University of Medical Science, Bushehr, Iran